In order to avoid misunderstandings, a brief description of each of the 9 hand lines in the picture, is given below:

Line 1 = extra crease on the distal phalange (beyond the distal interphalangeal crease)
Line 2 = extra crease on the middle phalange (in 1 or more fingers)
Line 3 = single crease on the pinky finger
Line 4 = extra crease on the thumb
Line 5 = ‘hockey-stick crease’
Line 6 = simian crease
Line 7 = Sydney crease
Line 8 = transverse hypothenar crease
Line 9 = secondary creases: unusually high density

The names of the 9 disorders are:

A = Alagille syndrome (= genetic disorder related to e.g. the liver, heart & kidney)
B = Coffin-Lowry syndrome (= genetic disorder: e.g. mental problems, health)
C = Down syndrome (= genetic disorder: trisomy 21, e.g. mental handicap, health)
F = Edward syndrome (= genetic disorder: trisomy 18, e.g. low rate of survival)
D = Fetal alcohol syndrome (= caused by alcohol abuse during pregnancy)
E = Fragile-X syndrome (= genetic disorder: Xq27, e.g. mental handicap, autism)
G = Pit-Rogers-Dank syndrome (= e.g. growth disorder, mental retardation)
H = Schizophrenia (= psychiatric disorder)
I = Sickle Cell Diseases (= blood disorder)

The QUIZ-task is very simple:
‘Which line (in the picture above) belongs to which disorder?’

(You can submit your answers as a response to this blog post, but you can also discuss the details at the Modern Hand Reading Forum, at:   The ‘Weird-Hand-Lines QUIZ’ – part 2)

By the way, quite a few ”clues’ for finding the right connections are provided in the section MEDICAL HAND ANALYSIS.

28 Characteristics of the hand in Fragile X syndrome (Xq27).

How to recognize the hand in Fragile X syndrome?

Alexander Rodewald presented in 1986 the very first ‘phantom picture’ describing the typical hand characteristics in Fragile X syndrome (e.g. including the simian crease or Sydney line). But more detailed ‘phantom pictures’ were never presented after the A. Rodewald et al. (1986) publication. However, this month (february 2010) an updated ‘phantom picture’ has become available – featuring 28 characteristics of the hand in Fragile X syndrome (+ a couple of other hand related characteristics).

What are typical hand characteristics in Fragile X syndrome?

A common characteristic is the presence of the famous ‘simian line‘; an alternative is the presence of a Sydney line.

Here one should especially notice the fingerprints of the 3rd finger (and the 2nd + 4th finger); often these demonstrate the presence of ‘radial loop’ patterns and/or arch patterns (the normal ‘ulnar loop’ patterns are less common in Fragile X syndrome) – combined with a ‘transverse’ pattern in the palmar ridge lines in the distal palmar zone.

The palm width (hand breadth) is relatively broad, and the palm length is usually a bit short. Finger length is relatively long compared to the palm length, but slightly short compared to the palm breadth.

NOTICE: The author of the new ‘phantom picture’ for Fragile X syndrome described a specific guideline which states that in most cases of Fragile X syndrome certain combinations of the 28 characteristics are found in both the fingers AND the palm of the hand!

More details available at:
How to use the ‘simian crease’ for recognizing Fragile X syndrome?

Photo: the hand of a baby hand with hyperextensible finger joints – often seen in Fragile X syndrome.
Hand of a baby hand with hyperextensible finger joints - often seen in fragile x syndrome.

Do you have a simian line?

November 2, 2008

The simian line.

The simian line.

A simian line variant.

A simian line variant.

A simian crease variant.

A simian crease variant.

A single transverse crease variant.

A single transverse crease variant.

A perfect simian line!

A perfect simian line!

The simian line

The simian line has been well-known since R.L. Down discovered in 1906 it’s significance in Down syndrome – it was his father who actually discovered the Down syndrome in 1866. Since then the simian line has been studied in many other aspects of life. The full article presents an overview of the most relevant aspects of the simian line.


A typical ‘simian line’ is characterized by the presence of a single line that runs across the palm of the hand. People normally have three major hand creases in their palms. Only when the simian line is present there are only two major creases. By the way, the simian line can manifest in various line constellations in the palm: some examples are present at the left.


The most popular alternative names for the ‘simian line’ are:

  • simian crease
  • single palmar transverse crease
  • simian fold

    The simian line appears to be related to rich scala of medical problems. Wrongdiagnosis.com presents a list of 93 causes of the simian crease, including Down syndrome, fragile-x syndrome and the cat-cry syndrome. However, one should never forget that the simian line (simian crease) is also found in the hands of perfectly healthy people!

    The simian line: a notorious hand crease!